Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400228 | 0.92 | LTB4R2 (0.35) | AKR1B1TP53TSHRALDH1A1 | |
| SCHEMBL8399344 | 0.91 | HDAC6 (0.37) | AKR1B1AKR1A1TP53 | |
| SCHEMBL8399085 | 0.91 | LTB4R2 (0.40) | TP53NPC1 | |
| SCHEMBL8399247 | 0.90 | AKR1B1 (0.32) | AKR1B1AKR1A1 | |
| SCHEMBL8399708 | 0.90 | AKR1B1 (0.35) | AKR1B1SMN1; SMN2TP53 | |
| SCHEMBL8399483 | 0.90 | HDAC6 (0.39) | SMN1; SMN2HTTNPC1ALDH1A1RAB9A | |
| SCHEMBL8395613 | 0.89 | AKR1B1 (0.36) | AKR1B1SMN1; SMN2HTTALOX15AKR1A1 | |
| SCHEMBL8398137 | 0.89 | RAB9A (0.40) | AKR1B1HTTTP53POLBNPC1 | |
| SCHEMBL8396627 | 0.89 | RXRA (0.34) | AKR1B1SMN1; SMN2HTTAKR1A1 | |
| SCHEMBL8399251 | 0.88 | TSHR (0.40) | AKR1B1HPGDAKR1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |