Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395876 | 0.91 | AKR1B1 (0.37) | AKR1B1HDAC6MEN1KMT2ANPC1 | |
| SCHEMBL8399715 | 0.90 | SMN1; SMN2 (0.39) | AKR1B1HDAC6MEN1KMT2AGRIN2D | |
| SCHEMBL8400332 | 0.89 | RAB9A (0.43) | AKR1B1HDAC6MEN1KMT2AMAPT | |
| SCHEMBL8397937 | 0.89 | AKR1B1 (0.38) | AKR1B1HDAC6MEN1KMT2AMAPT | |
| SCHEMBL8400428 | 0.88 | AKR1B1 (0.41) | AKR1B1HDAC6MEN1KMT2AMAPT | |
| SCHEMBL8398067 | 0.86 | AKR1B1 (0.46) | AKR1B1HDAC6MEN1KMT2AMAPT | |
| SCHEMBL8395578 | 0.86 | AKR1B1 (0.39) | AKR1B1HDAC6MEN1KMT2AMAPT | |
| SCHEMBL8396282 | 0.86 | AKR1B1 (0.40) | AKR1B1HDAC6MEN1KMT2ANPC1 | |
| SCHEMBL8397855 | 0.86 | AKR1B1 (0.40) | AKR1B1HDAC6MEN1KMT2AMAPT | |
| SCHEMBL8399147 | 0.85 | MTNR1A (0.39) | AKR1B1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |