Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394885 | 1.00 | HTT (0.48) | HTTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8394004 | 1.00 | HTT (0.48) | HTTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8392923 | 0.98 | HTT (0.49) | HTTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8392664 | 0.93 | HTT (0.50) | HTTMEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8395938 | 0.84 | L3MBTL1 (0.52) | MEN1KMT2APOLBSMN1; SMN2HPGD | |
| SCHEMBL8393256 | 0.84 | L3MBTL1 (0.52) | MEN1KMT2APOLBSMN1; SMN2HPGD | |
| SCHEMBL8391316 | 0.84 | L3MBTL1 (0.52) | MEN1KMT2APOLBSMN1; SMN2HPGD | |
| SCHEMBL8394587 | 0.83 | L3MBTL1 (0.53) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8396609 | 0.83 | L3MBTL1 (0.53) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8392303 | 0.83 | L3MBTL1 (0.53) | MEN1KMT2ASMN1; SMN2HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0392317-B1 | Benzimidazoles, drugs containing these compounds and process for their preparation | THOMAE GMBH DR K (DE) | 1996-01-03 | — | — | EP | disclosed |