Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.58 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8391959 | 0.90 | PPARG (0.59) | PPARGAGTR1AGTR2MEN1LMNA | |
| SCHEMBL8393393 | 0.89 | PPARG (0.56) | PPARGAGTR1AGTR2MEN1LMNA | |
| SCHEMBL8944623 | 0.89 | MEN1 (0.51) | PPARGAGTR1AGTR2MEN1LMNA | |
| SCHEMBL8395681 | 0.89 | PPARG (0.76) | PPARGAGTR1AGTR2 | |
| SCHEMBL8396220 | 0.87 | AGTR1 (0.77) | PPARGAGTR1AGTR2 | |
| SCHEMBL9042725 | 0.86 | MEN1 (0.53) | PPARGAGTR1AGTR2MEN1LMNA | |
| SCHEMBL8393379 | 0.86 | PPARG (0.76) | PPARGAGTR1AGTR2MEN1LMNA | |
| SCHEMBL8396783 | 0.86 | PPARG (0.78) | PPARGAGTR1AGTR2 | |
| SCHEMBL8392509 | 0.85 | PPARG (0.60) | PPARGAGTR1AGTR2 | |
| SCHEMBL8392428 | 0.82 | POLB (0.60) | PPARGAGTR1AGTR2MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |