Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396648 | 0.89 | PPARG (0.60) | MEN1TSHRKMT2ANPSR1LMNA | |
| SCHEMBL8391959 | 0.81 | PPARG (0.59) | MEN1TSHRKMT2ANPSR1LMNA | |
| SCHEMBL9042725 | 0.79 | MEN1 (0.53) | MEN1TSHRKMT2ANPSR1LMNA | |
| SCHEMBL8393379 | 0.79 | PPARG (0.76) | MEN1TSHRKMT2ANPSR1LMNA | |
| SCHEMBL8393393 | 0.79 | PPARG (0.56) | MEN1TSHRKMT2ANPSR1LMNA | |
| SCHEMBL8395681 | 0.77 | PPARG (0.76) | PPARGAGTR2AGTR1 | |
| SCHEMBL8396220 | 0.76 | AGTR1 (0.77) | PPARGAGTR2AGTR1 | |
| SCHEMBL8396783 | 0.75 | PPARG (0.78) | PPARGAGTR2AGTR1 | |
| SCHEMBL8392509 | 0.74 | PPARG (0.60) | PPARGAGTR2AGTR1 | |
| SCHEMBL9043566 | 0.74 | AGTR2 (0.51) | MEN1TSHRKMT2ANPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |