Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8397111

CCc1cccc(C(=O)c2ccccc2)c1CC.N

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 2/20 0.50
GAA P10253 1/20 0.47
MAPT P10636 1/20 0.47
CLCN2 P51788 1/20 0.45
ALDH1A1 P00352 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.44
ATM Q13315 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
POLB P06746 1/20 0.44
CYP19A1 P11511 1/20 0.43
PTGS1 P23219 1/20 0.43
PTGS2 P35354 1/20 0.43
KMT2A Q03164 1/20 0.42
HPGD P15428 1/20 0.42
MYC P01106 1/20 0.42
ELANE P08246 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9625731 0.98 AKR1C3 (0.52) AKR1C3GAAMAPTCLCN2ALDH1A1
Acetic Acid SCHEMBL28345622 0.95 AKR1C3 (0.48) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL28403834 0.95 AKR1C3 (0.53) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL27783507 0.92 AKR1C3 (0.46) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL27670335 0.88 AKR1C3 (0.46) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL7768843 0.86 AKR1C3 (0.60) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL28552463 0.85 KMO (0.49) GAAMAPTL3MBTL1ATMTDP1
SCHEMBL29881091 0.85 AKR1C3 (0.57) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL723171 0.85 AKR1C3 (0.57) AKR1C3GAAMAPTCLCN2ALDH1A1
SCHEMBL10915002 0.85 GABRA1 (0.50) GAAMAPTCLCN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0917544-A1 WATER SOLUBLE AND OXYGEN-IMPERMEABLE POLYMERIC LAYERS Kodak Polychrome Graphics LLC (US) 1999-05-26 EP disclosed
WO-1998013394-A1 WATER SOLUBLE AND OXYGEN-IMPERMEABLE POLYMERIC LAYERS SUN CHEMICAL CORPORATION (US) 1998-04-02 WO disclosed