Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 15/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 14/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.41 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400653 | 0.90 | CDK1 (0.51) | HSP90AB1HSP90AA1HPRT1CYP2C19 | |
| SCHEMBL14244161 | 0.88 | HSP90AB1 (0.45) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL6837988 | 0.81 | HDAC1 (0.44) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL8397115 | 0.81 | FGFR1 (0.61) | — | |
| SCHEMBL1566036 | 0.78 | FGFR1 (0.63) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL30759944 | 0.78 | FGFR1 (0.63) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL8709241 | 0.77 | HSP90AB1 (0.43) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL24316894 | 0.76 | POLB (0.56) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL8400863 | 0.76 | SLC22A6 (0.47) | HSP90AB1HSP90AA1HDAC6HDAC1HDAC4 | |
| SCHEMBL7590077 | 0.75 | CYP2C19 (0.53) | HPRT1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874577-A | Method for the preparing 9-12-(Diethoxyphosphonomethoxy)ethyl!adenine and analogues thereof | MEDICHEM RESEARCH, INC. (US) | 1999-02-23 | — | — | US | disclosed |