Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.33 |
| ▸ | PDE5A | O76074 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 3/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397096 | 0.87 | CTSL (0.41) | CTSLCTSBPDE10APDE5APDE4A | |
| SCHEMBL1387933 | 0.84 | YTHDC1 (0.41) | CTSLCTSBPDE10AYTHDC1PDE4A | |
| Hydrochloric Acid SCHEMBL7027845 | 0.83 | YTHDC1 (0.40) | CTSLCTSBPDE10AYTHDC1PDE4A | |
| SCHEMBL1388063 | 0.83 | CTSL (0.42) | CTSLYTHDC1 | |
| Hydrochloric Acid SCHEMBL7030023 | 0.82 | CTSL (0.41) | CTSLYTHDC1 | |
| SCHEMBL8393039 | 0.80 | CDK2 (0.39) | CTSLPDE10A | |
| SCHEMBL1388327 | 0.80 | MAPK13 (0.34) | YTHDC1 | |
| Hydrochloric Acid SCHEMBL7028127 | 0.79 | MAPK13 (0.33) | YTHDC1 | |
| SCHEMBL1388397 | 0.79 | PDE10A (0.43) | PDE10AYTHDC1PDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL7030283 | 0.78 | PDE10A (0.42) | PDE10AYTHDC1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0916673-A1 | 6-Amino purine derivatives having PDE-IV inhibition activity | Euroceltique S.A. (LU) | 1999-05-19 | — | — | EP | claimed |