Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 0.53 |
| ▸ | CTSK | P43235 | 16/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398617 | 0.86 | CTSS (0.53) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL269930 | 0.82 | ACE (0.58) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL269929 | 0.82 | ACE (0.58) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL873556 | 0.82 | ACE (0.58) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL8396408 | 0.81 | CTSS (0.47) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL8398398 | 0.81 | MDM4 (0.43) | TP53 | |
| SCHEMBL268270 | 0.81 | CTSS (0.57) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL8398313 | 0.80 | CTSS (0.48) | CTSSCTSKCTSLCTSBSCN9A | |
| SCHEMBL8399891 | 0.78 | DPP4 (0.41) | — | |
| SCHEMBL16458597 | 0.78 | CTSS (0.48) | CTSSCTSKCTSLCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |