Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 10/20 | 0.47 |
| ▸ | CTSK | P43235 | 9/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.44 |
| ▸ | CTSL | P07711 | 3/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398313 | 0.85 | CTSS (0.48) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL8397274 | 0.81 | CTSS (0.53) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL8398617 | 0.79 | CTSS (0.53) | CTSSCTSKCTSLCTSBMAPT | |
| SCHEMBL8395483 | 0.76 | CTSK (0.46) | CTSSCTSKCTSLCTSBCACNA1B | |
| SCHEMBL8133157 | 0.76 | REN (0.56) | CTSKREN | |
| SCHEMBL8133154 | 0.76 | REN (0.56) | CTSKREN | |
| SCHEMBL269929 | 0.75 | ACE (0.58) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL873556 | 0.75 | ACE (0.58) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL269930 | 0.75 | ACE (0.58) | CTSSCTSKSCN9ACTSLCTSB | |
| SCHEMBL268270 | 0.74 | CTSS (0.57) | CTSSCTSKCTSLCTSBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |