SCHEMBL8397382

SCHEMBL8397382

COc1cccc(C)c1Nc1c(Cl)c2c(c(Cl)c1Nc1c(C)cccc1OC)C(=O)c1ccccc1C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.47
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
KDM4E B2RXH2 2/20 0.47
USP2 O75604 1/20 0.47
DUSP3 P51452 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
POLB P06746 2/20 0.42
MAPK1 P28482 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
DHODH Q02127 1/20 0.42
RAB9A P51151 4/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
NPC1 O15118 2/20 0.41
ADORA2A P29274 2/20 0.41
THRB P10828 2/20 0.41
FGB P02675 1/20 0.41
PPARG P37231 1/20 0.41
NCOA2 Q15596 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29502773 1.00 MAPT (0.47) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL21816992 0.85 CYP1A1 (0.44) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL29502784 0.84 MAPT (0.47) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL6651932 0.84 MAPT (0.47) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL6654425 0.82 MAPT (0.45) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL28396697 0.75 MAPT (0.41) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL29460865 0.74 MAPT (0.53) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL15883199 0.72 ALDH1A1 (0.55) MAPTALDH1A1KMT2AKDM4EMAPK1
SCHEMBL11851605 0.71 MAPT (0.45) MAPTALDH1A1MEN1KMT2AKDM4E
SCHEMBL16001849 0.70 TAAR1 (0.51) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250251665-A1 PHOTOSENSITIVE RESIN COMPOSITION, PHOTOSENSITIVE RESIN FILM, PHOTOSENSITIVE DRY FILM, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-08-07 US disclosed
EP-3982170-B1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO (JP) 2023-12-06 EP disclosed
US-11634579-B2 Resin composition, molded body, optical layer, cover member and moving body SUMITOMO BAKELITE CO., LTD. (JP) 2023-04-25 US disclosed
EP-3719085-B1 RESIN COMPOSITION, OPTICAL LAYER, COVER MEMBER AND MOVABLE BODY SUMITOMO BAKELITE CO (JP) 2022-10-26 EP disclosed
US-11402667-B2 Optical sheet and optical component SUMITOMO BAKELITE CO., LTD. (JP) 2022-08-02 US disclosed
US-11345132-B2 Optical sheet and optical component SUMITOMO BAKELITE CO., LTD. (JP) 2022-05-31 US disclosed
EP-3982170-A1 OPTICAL SHEET AND OPTICAL COMPONENT Sumitomo Bakelite Co.Ltd. (JP) 2022-04-13 EP disclosed
US-20220107447-A1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO., LTD. (JP) 2022-04-07 US disclosed
US-20220043283-A1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO., LTD. (JP) 2022-02-10 US disclosed
EP-3690504-B1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO (JP) 2022-01-12 EP disclosed
EP-3690502-B1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO (JP) 2022-01-05 EP disclosed
US-11119260-B2 Optical sheet and optical component SUMITOMO BAKELITE CO., LTD. (JP) 2021-09-14 US disclosed
US-20200361178-A1 RESIN COMPOSITION, OPTICAL LAYER, COVER MEMBER, AND MOVING BODY SUMITOMO BAKELITE CO., LTD. (JP) 2020-11-19 US disclosed
EP-3719085-A1 RESIN COMPOSITION, OPTICAL LAYER, COVER MEMBER AND MOVABLE BODY Sumitomo Bakelite Co.Ltd. (JP) 2020-10-07 EP disclosed
US-20200310015-A1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO., LTD. (JP) 2020-10-01 US disclosed
US-20200249378-A1 OPTICAL SHEET AND OPTICAL COMPONENT SUMITOMO BAKELITE CO., LTD. (JP) 2020-08-06 US disclosed
EP-3690502-A1 OPTICAL SHEET AND OPTICAL COMPONENT Sumitomo Bakelite Co.Ltd. (JP) 2020-08-05 EP disclosed
EP-3690504-A1 OPTICAL SHEET AND OPTICAL COMPONENT Sumitomo Bakelite Co., Ltd. (JP) 2020-08-05 EP disclosed
US-5968688-A RESINS AND DYES FOR COLOR FILTERS NIPPON SHOKUBAI CO., LTD. (JP) 1999-10-19 US disclosed
EP-0833203-A1 Color filter grade photosensitive resin coloring composition, and color filter using the same NIPPON SHOKUBAI CO., LTD. (JP) 1998-04-01 EP disclosed