SCHEMBL21816992

SCHEMBL21816992

COc1cccc(C)c1Nc1cc(Cl)c2c(c1Cl)C(=O)c1ccccc1C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 1/20 0.44
CYP1A2 P05177 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
CASP3 P42574 2/20 0.44
PAX8 Q06710 2/20 0.44
SENP8 Q96LD8 2/20 0.44
SENP7 Q9BQF6 2/20 0.44
SENP6 Q9GZR1 2/20 0.44
APAF1 O14727 1/20 0.44
ACLY P53396 1/20 0.42
CLCN2 P51788 2/20 0.42
MAPT P10636 5/20 0.41
KDM4E B2RXH2 2/20 0.41
ALDH1A1 P00352 2/20 0.41
USP2 O75604 1/20 0.41
DUSP3 P51452 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TP53 P04637 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8397382 0.85 MAPT (0.47) CYP1A2MEN1KMT2ACASP3PAX8
SCHEMBL29502773 0.85 MAPT (0.47) CYP1A2MEN1KMT2ACASP3PAX8
SCHEMBL28396697 0.77 MAPT (0.41) CYP1A2MEN1KMT2AMAPTKDM4E
SCHEMBL29502784 0.75 MAPT (0.47) CYP1A2MEN1KMT2AAPAF1MAPT
SCHEMBL6651932 0.75 MAPT (0.47) CYP1A2MEN1KMT2AAPAF1MAPT
SCHEMBL8942893 0.73 CYP1A1 (0.70) CYP1A1CYP1A2MEN1KMT2ACASP3
SCHEMBL6654425 0.73 MAPT (0.45) CYP1A2MEN1KMT2AAPAF1MAPT
SCHEMBL16001849 0.70 TAAR1 (0.51)
SCHEMBL6158366 0.69 DHODH (0.55) CYP1A2MEN1KMT2ACASP3SENP7
SCHEMBL5451202 0.68 ALDH1A1 (0.58) CYP1A2MEN1KMT2AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113661065-B Resin composition, molded body, optical layer, cover member, and moving body 住友电木株式会社 2022-05-10 CN disclosed
CN-113661065-A Resin composition, molded body, optical layer, cover member, and moving body 住友电木株式会社 2021-11-16 CN disclosed
CN-111630121-B Resin composition, optical layer, cover member, and moving object 住友电木株式会社 2021-09-07 CN disclosed
CN-113302525-A Optical sheet and optical element 住友电木株式会社 2021-08-24 CN disclosed
CN-111630121-A Resin composition, optical layer, cover member, and moving object 住友电木株式会社 2020-09-04 CN disclosed
CN-111164467-A Optical sheet and optical element 住友电木株式会社 2020-05-15 CN disclosed
WO-2020066996-A1 RESIN COMPOSITION, OPTICAL LAYER, COVER MEMBER AND MOVABLE BODY 住友ベークライト株式会社 2020-04-02 WO disclosed