Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL8397553

O=C(O)C(F)(F)F.c1scc2c1CNC2

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 4/20 0.33
PKM P14618 1/20 0.31
TSHR P16473 1/20 0.31
SLC6A1 P30531 1/20 0.31
SLC6A13 Q9NSD5 1/20 0.31
UHRF1 Q96T88 1/20 0.30
IRAK4 Q9NWZ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL4782632 0.78 PNMT (0.43) KDM1A
SCHEMBL3623298 0.78
Trifluoroacetic Acid SCHEMBL5708755 0.76 KDM1A (0.49) KDM1A
Trifluoroacetic Acid SCHEMBL20958677 0.73 PKM (0.32) KDM1APKM
Trifluoroacetic Acid SCHEMBL23163788 0.72 KDM1A (0.33) KDM1APKM
Trifluoroacetic Acid SCHEMBL28336891 0.72 PKM (0.31) KDM1APKM
Trifluoroacetic Acid SCHEMBL23577874 0.69 PKM (0.30) PKM
Trifluoroacetic Acid SCHEMBL21639975 0.67 HRH4 (0.30)
Trifluoroacetic Acid SCHEMBL4391008 0.65 TSHR (0.38) KDM1APKMTSHR
Trifluoroacetic Acid SCHEMBL15355467 0.65 TSHR (0.37) KDM1APKMTSHRSLC6A1SLC6A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5869518-A USEFUL IN THE TREATMENT OF OBESITY AND HYPERGLYCEMIA SYNTHELABO (FR) 1999-02-09 US disclosed