Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.73 |
| ▸ | RAB9A | P51151 | 9/20 | 0.66 |
| ▸ | NPC1 | O15118 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.66 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 3/20 | 0.66 |
| ▸ | MMP9 | P14780 | 2/20 | 0.66 |
| ▸ | MMP8 | P22894 | 2/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.65 |
| ▸ | RELA | Q04206 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | GLA | P06280 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7836371 | 0.89 | APP (0.75) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL6284593 | 0.84 | APP (0.69) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL29406270 | 0.84 | APP (0.69) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL4593608 | 0.84 | APP (0.69) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL1726512 | 0.84 | APP (1.00) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL1978135 | 0.84 | APP (0.69) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL4592891 | 0.84 | APP (0.69) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL1326042 | 0.84 | APP (0.69) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL12227064 | 0.84 | APP (0.69) | APPRAB9ANPC1KDM4EMAPT | |
| SCHEMBL2240330 | 0.81 | APP (0.65) | APPRAB9ANPC1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721336-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-07-17 | — | — | EP | claimed |
| WO-1995006469-A1 | BENZAZOLE COMPOUNDS FOR USE IN THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1995-03-09 | — | — | WO | claimed |
| US-5874431-A | ANTITUMOR AGENTS; BREAST CANCER | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1999-02-23 | — | — | US | disclosed |