Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHF8 | Q9UPP1 | 5/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | KDM5C | P41229 | 3/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397757 | 0.70 | — | — | |
| SCHEMBL1117822 | 0.69 | — | — | |
| Water SCHEMBL8221742 | 0.68 | — | — | |
| SCHEMBL7342409 | 0.67 | RAB9A (0.30) | — | |
| SCHEMBL2801118 | 0.64 | — | — | |
| Water SCHEMBL7805742 | 0.63 | — | — | |
| SCHEMBL11098112 | 0.62 | — | — | |
| SCHEMBL4977396 | 0.60 | PHF8 (0.57) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL28461081 | 0.60 | PHF8 (0.57) | PHF8KDM2AKDM4EKDM5CEGLN1 | |
| SCHEMBL4977586 | 0.57 | PHF8 (0.52) | PHF8KDM2AKDM4EKDM5CEGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874424-A | Inhibitors of interleukin-1β converting enzyme | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1999-02-23 | — | — | US | disclosed |