Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.60 |
| ▸ | HTR3E | A5X5Y0 | 8/20 | 0.55 |
| ▸ | HTR3B | O95264 | 8/20 | 0.55 |
| ▸ | HTR3A | P46098 | 8/20 | 0.55 |
| ▸ | HTR3D | Q70Z44 | 8/20 | 0.55 |
| ▸ | HTR3C | Q8WXA8 | 8/20 | 0.55 |
| ▸ | SLC22A2 | O15244 | 2/20 | 0.50 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.50 |
| ▸ | SLC22A3 | O75751 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8334511 | 0.79 | NOS1 (0.49) | NOS1CA12CA2GLO1CA9 | |
| SCHEMBL11879362 | 0.77 | POLB (0.58) | NOS1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL14257233 | 0.77 | NOS1 (0.44) | NOS1CA12CA2GLO1CA9 | |
| SCHEMBL7049487 | 0.77 | NOS1 (0.44) | NOS1CA12CA2GLO1CA9 | |
| SCHEMBL18856687 | 0.76 | NOS1 (0.43) | NOS1CA12CA2GLO1CA9 | |
| SCHEMBL18856688 | 0.76 | NOS1 (0.43) | NOS1CA12CA2GLO1CA9 | |
| SCHEMBL6724203 | 0.74 | SIGMAR1 (0.54) | NOS1CA12CA2CA9 | |
| SCHEMBL10051059 | 0.73 | CA1 (0.55) | CA2 | |
| SCHEMBL1772255 | 0.73 | CYP3A4 (0.42) | NOS1TAAR1CA12CA2GLO1 | |
| SCHEMBL14257779 | 0.71 | MIF (0.45) | NOS1CA12CA2GLO1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | claimed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | claimed |