Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.44 |
| ▸ | GPX4 | P36969 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8398181 | 0.85 | AKR1B1 (0.44) | SYKGPX4HDAC4MEF2DRPS6KA2 | |
| SCHEMBL8396283 | 0.83 | SYK (0.45) | SYKGPX4HDAC4MEF2DEP300 | |
| SCHEMBL8395622 | 0.83 | KDM4E (0.41) | HDAC4MEF2DPIM1MAPTKDM4E | |
| SCHEMBL8399152 | 0.83 | ALDH1A1 (0.40) | SYKGPX4HDAC4MEF2DEP300 | |
| SCHEMBL8398019 | 0.82 | GAA (0.43) | SYKPIM1MAPTKDM4ELMNA | |
| SCHEMBL8395768 | 0.81 | MEN1 (0.35) | HDAC4MEF2DPIM1MAPTKDM4E | |
| SCHEMBL8398085 | 0.80 | AKR1B1 (0.44) | PIM1MAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8398879 | 0.77 | AKR1B1 (0.37) | PIM1MAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL8399257 | 0.76 | SYK (0.44) | SYKGPX4HDAC4MEF2DEP300 | |
| SCHEMBL8399104 | 0.75 | MAPT (0.39) | PIM1MAPTKDM4ELMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |