Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.45 |
| ▸ | GPX4 | P36969 | 1/20 | 0.41 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | MEF2D | Q14814 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399257 | 0.86 | SYK (0.44) | SYKGPX4RPS6KA2HDAC4MEF2D | |
| SCHEMBL8396597 | 0.83 | NOS1 (0.43) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL8398181 | 0.83 | AKR1B1 (0.44) | SYKGPX4RPS6KA2HDAC4MEF2D | |
| SCHEMBL8398153 | 0.83 | SYK (0.44) | SYKGPX4RPS6KA2HDAC4MEF2D | |
| SCHEMBL8395544 | 0.82 | GAA (0.43) | SYKMAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL8396076 | 0.82 | MEN1 (0.34) | HDAC4MEF2DMAPTKMT2AMEN1 | |
| SCHEMBL8395427 | 0.81 | EGFR (0.38) | MAPTKMT2AMEN1NPC1 | |
| SCHEMBL8399066 | 0.81 | CYP1A2 (0.35) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8399268 | 0.79 | SMN1; SMN2 (0.37) | MAPTTDP1KMT2AMEN1NPC1 | |
| SCHEMBL8397890 | 0.78 | RAB9A (0.37) | MAPTNPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |