Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 8/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARD | Q03181 | 4/20 | 0.36 |
| ▸ | FAAH | O00519 | 5/20 | 0.36 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | GOT1 | P17174 | 1/20 | 0.34 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8570276 | 0.93 | PPARG (0.38) | PPARGPPARAPPARDFAAHCNR2 | |
| SCHEMBL8431850 | 0.84 | PPARG (0.41) | PPARGPPARAPPARDCNR2PKM | |
| SCHEMBL8433276 | 0.84 | RARA (0.44) | MEN1KMT2APGRNR1I2LMNA | |
| SCHEMBL8398167 | 0.83 | IKBKB (0.38) | PPARGPPARAPPARDFAAHCNR2 | |
| SCHEMBL8394296 | 0.82 | CNR2 (0.35) | FAAHCNR2P2RX7MEN1KMT2A | |
| SCHEMBL8432026 | 0.81 | HIF1A (0.37) | PPARGPPARAPPARDCNR2PGR | |
| SCHEMBL8434104 | 0.80 | S1PR1 (0.33) | MEN1KMT2APGRNR1I2LMNA | |
| SCHEMBL8397837 | 0.80 | — | — | |
| SCHEMBL8521547 | 0.80 | RARA (0.31) | PPARGMEN1KMT2APGRNR1I2 | |
| SCHEMBL8397882 | 0.79 | RARG (0.48) | CNR2MEN1KMT2APGRNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | disclosed |