Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 7/20 | 0.32 |
| ▸ | CES1 | P23141 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603973 | 0.91 | CES2 (0.43) | CES2LPAR1LPAR3FDPSTSHR | |
| SCHEMBL8393136 | 0.78 | CES2 (0.41) | CES2LPAR1LPAR3SMPD1FDPS | |
| SCHEMBL28481318 | 0.74 | TSHR (0.44) | CES2TSHRTHRBFAAHCES1 | |
| SCHEMBL294511 | 0.74 | — | — | |
| SCHEMBL20966349 | 0.74 | TSHR (0.61) | TSHRTHRBMEN1KMT2AHSD17B10 | |
| SCHEMBL19221488 | 0.74 | TSHR (0.61) | TSHRTHRBMEN1KMT2AHSD17B10 | |
| SCHEMBL10608047 | 0.74 | TSHR (0.61) | TSHRTHRBMEN1KMT2AHSD17B10 | |
| SCHEMBL113425 | 0.74 | TSHR (0.61) | TSHRTHRBMEN1KMT2AHSD17B10 | |
| SCHEMBL9938856 | 0.74 | TSHR (0.61) | TSHRTHRBMEN1KMT2AHSD17B10 | |
| SCHEMBL7198783 | 0.74 | TSHR (0.61) | TSHRTHRBMEN1KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650969-B1 | A Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-05-26 | — | — | EP | disclosed |