Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.34 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.32 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9572319 | 0.85 | SLC7A5 (0.42) | SLC7A5SCN9ALARS1AAK1ANPEP | |
| SCHEMBL8972083 | 0.77 | DPP7 (0.42) | DPP4 | |
| SCHEMBL9572330 | 0.76 | METAP2 (0.39) | SLC7A5SCN9ALARS1ANPEPRNPEP | |
| SCHEMBL8398395 | 0.74 | CAPN1 (0.33) | CAPN1ANPEPCTSD | |
| Hydrochloric Acid SCHEMBL15527937 | 0.71 | BIRC2 (0.46) | — | |
| SCHEMBL9572297 | 0.71 | SLC7A5 (0.38) | SLC7A5SCN9ALARS1AAK1ANPEP | |
| SCHEMBL15613199 | 0.70 | SLC7A5 (0.44) | SLC7A5SCN9ALARS1AAK1ANPEP | |
| SCHEMBL25154881 | 0.70 | SLC7A5 (0.47) | SLC7A5SCN9ALARS1AAK1ANPEP | |
| SCHEMBL15412847 | 0.70 | SLC7A5 (0.52) | SLC7A5GRIK1GRIK2CAPN1LARS1 | |
| SCHEMBL10296149 | 0.69 | SLC7A5 (0.54) | SLC7A5SCN9ALARS1AAK1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |