SCHEMBL8972083

SCHEMBL8972083

CCCCC(NC(=O)[C@@H](N)CC(C)C)C(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DPP7 Q9UHL4 11/20 0.42
DPP9 Q86TI2 9/20 0.42
DPP8 Q6V1X1 9/20 0.42
DPP4 P27487 6/20 0.42
SLC15A1 P46059 1/20 0.42
REN P00797 1/20 0.40
CTSK P43235 1/20 0.38
TLR2 O60603 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
BIRC2 Q13490 2/20 0.36
SLC1A3 P43003 1/20 0.36
SLC1A2 P43004 1/20 0.36
SLC1A1 P43005 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9572334 0.89 DPP7 (0.42) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL9572312 0.86 DPP7 (0.40) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL9572319 0.85 SLC7A5 (0.42) SLC1A3SLC1A2
SCHEMBL9572330 0.82 METAP2 (0.39)
SCHEMBL8972038 0.81 ALDH1A1 (0.44) RENCTSKBIRC2
SCHEMBL8972090 0.81 BIRC2 (0.43) RENCTSKBIRC2
SCHEMBL8971772 0.80 BIRC2 (0.42) RENCTSKBIRC2
SCHEMBL8971431 0.79 BIRC2 (0.41) RENBIRC2
SCHEMBL7371457 0.79 L3MBTL1 (0.39) DPP7DPP9DPP8DPP4SLC15A1
SCHEMBL7324513 0.78 BIRC2 (0.51) DPP7DPP9DPP8DPP4SLC15A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0543310-B1 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LTD (JP) 1996-03-27 EP disclosed
US-5395824-A Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LIMITED (JP) 1995-03-07 US disclosed
EP-0543310-A2 Dipeptide derivative and prophylactic and therapeutic agent for bone diseases containing the same SUNTORY LIMITED (JP) 1993-05-26 EP disclosed