⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970934 | 0.82 | LMNA (0.44) | — | |
| SCHEMBL4284663 | 0.82 | LMNA (0.44) | — | |
| SCHEMBL4076760 | 0.82 | LMNA (0.44) | — | |
| SCHEMBL4290542 | 0.82 | LMNA (0.44) | — | |
| SCHEMBL18532443 | 0.82 | LMNA (0.35) | — | |
| SCHEMBL5697239 | 0.82 | LMNA (0.35) | — | |
| Hydrochloric Acid SCHEMBL3670637 | 0.79 | LMNA (0.41) | — | |
| Hydrochloric Acid SCHEMBL3672162 | 0.79 | LMNA (0.33) | — | |
| Hydrochloric Acid SCHEMBL3672161 | 0.79 | LMNA (0.33) | — | |
| Hydrochloric Acid SCHEMBL3675135 | 0.79 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5976382-A | CROSSLINKING AN OLEFIN OR ALKYL VINYL ETHER-MALEIC ANHYDRIDE COPOLYMER WITH A DIAMINE. SEPARATION OF PROTEIN/POLYMER MATRIX WITH SODIUM DODECYL SULFATE. | LIGOCHEM, INC. (US) | 1999-11-02 | — | — | US | disclosed |
| EP-0750644-B1 | WATER INSOLUBLE CROSS-LINKED POLYCARBONIC ACID COMPOSITIONS | LIGOCHEM INC (US) | 1998-06-10 | — | — | EP | disclosed |
| US-5534597-A | CROSSLINKING A MALEIC ANHYDRIDE COPOLYMER WITH AN A,W-DIAMINOHYDROXYALKANE | AFFINITY TECHNOLOGY, INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5453493-A | Maleic anhydride copolymer crosslinked with a hydroxy or polyhydroxy diamine | AFFINITY TECHNOLOGY, INC. (US) | 1995-09-26 | — | — | US | disclosed |
| US-5294681-A | Maleic anhydride copolymer crosslinked w/diamino alcohol | AFFINITY TECHNOLOGY, INC. (US) | 1994-03-15 | — | — | US | disclosed |
| US-5130119-A | Sulfonamide or hydroxy fluorine substituted benzene for medical diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1992-07-14 | — | — | US | disclosed |