SCHEMBL5697239

SCHEMBL5697239

NCC(O)C(O)C(O)CN

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CETP P11597 1/20 0.35
TDP1 Q9NUW8 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GABRR1 P24046 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18532443 1.00 LMNA (0.35) LMNAL3MBTL1CETPTDP1ALDH1A1
Hydrochloric Acid SCHEMBL3672161 0.96 LMNA (0.33) LMNAL3MBTL1CETPTDP1ALDH1A1
Hydrochloric Acid SCHEMBL3672162 0.96 LMNA (0.33) LMNAL3MBTL1CETPTDP1ALDH1A1
SCHEMBL3970934 0.92 LMNA (0.44) LMNAL3MBTL1CETPTDP1ALDH1A1
SCHEMBL4076760 0.92 LMNA (0.44) LMNAL3MBTL1CETPTDP1ALDH1A1
SCHEMBL4290542 0.92 LMNA (0.44) LMNAL3MBTL1CETPTDP1ALDH1A1
SCHEMBL4284663 0.92 LMNA (0.44) LMNAL3MBTL1CETPTDP1ALDH1A1
Hydrochloric Acid SCHEMBL3675135 0.88 LMNA (0.41) LMNAL3MBTL1CETPTDP1ALDH1A1
Hydrochloric Acid SCHEMBL3670637 0.88 LMNA (0.41) LMNAL3MBTL1CETPTDP1ALDH1A1
SCHEMBL14624506 0.87 LMNA (0.59) LMNAL3MBTL1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2964224-B1 POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT POLYACTIVA PTY LTD (AU) 2024-07-03 EP disclosed
US-20110046982-A1 METHODS AND COMPOSITIONS RELATED TO VIRAL INHIBITION CLEMSON UNIVERSITY RESEARCH FOUNDATION (CURF) (US) 2011-02-24 US disclosed
EP-1046649-B1 Solid phase nucleic acid labeling by transamination ABBOTT MOLECULAR INC (US) 2006-06-28 EP disclosed
US-6569626-B2 Hybridization; binding Dna segments; labeling; detection fluorescence VYSIS, INC. 2003-05-27 US disclosed
US-20020025523-A1 Probe compositions for chromosome identification and methods BITTNER MICHAEL L (US) 2002-02-28 US disclosed
US-6277569-B1 STAINING MIXED DNA SEGMENTS FOR DETECTION OF AT LEAST THREE PRESELECTED TARGET CHROMOSOMES OR REGIONS BY IN SITU HYBRIDIZATION USING MULTIPLE PROBES VYSIS, INC. 2001-08-21 US disclosed
US-6194563-B1 TRANSAMINATING THE CYTIDINE BASE OF SOLID-SUPPORT-IMMOBILIZED NUCLEIC ACID WITH A REACTIVE GROUP TO FORM A COVALENT LINKAGE, THEN LINKING A DETECTABLE LABEL TO REACTIVE GROUP; FLUORESCENT HYBRIDIZATION PROBES VYSIS, INC. 2001-02-27 US disclosed
EP-1046649-A1 Solid phase nucleic acid labeling by transamination VYSIS, Inc. (US) 2000-10-25 EP disclosed
EP-0558732-B1 PRODUCTION OF CHROMOSOME REGION SPECIFIC DNA SEQUENCES AND TRANSAMINATION AMOCO CORP (US) 1999-03-03 EP disclosed
EP-0558740-B1 PROBE COMPOSITION FOR GENOME IDENTIFICATION AND METHODS VYSIS INC (US) 1998-08-05 EP disclosed
US-5789161-A Methods for genome identification using direct label probe composition AMOCO CORPORATION (US) 1998-08-04 US disclosed
US-5776688-A Methods for detection by in situ hybridization of multiple chromosomes or regions thereof VYSIS, INC. (US) 1998-07-07 US disclosed
US-5663319-A Probe compositions for chromosome identification and methods VYSIS, INC. (US) 1997-09-02 US disclosed
EP-0787805-A2 Probe compositions for chromosome identification and method AMOCO CORPORATION (US) 1997-08-06 EP disclosed
EP-0549709-B1 PROBE COMPOSITIONS FOR CHROMOSOME IDENTIFICATION AND METHODS AMOCO CORP (US) 1997-01-29 EP disclosed
US-5506350-A IN PRESENCE OF A TRIFLUOROACETATE CHAOTROPE BITTNER MICHAEL L (US) 1996-04-09 US disclosed
US-5491224-A FOR IN SITU HYBRIDIZATION ENUMERATIONS OF SPECIFIC CHROMOSOME CENTROMERES VYSIS, INC. 1996-02-13 US disclosed
EP-0558740-A1 PROBE COMPOSITION FOR GENOME IDENTIFICATION AND METHODS VYSIS, Inc. (US) 1993-09-08 EP disclosed
WO-1993006245-A1 PROBE COMPOSITION FOR GENOME IDENTIFICATION AND METHODS AMOCO CORPORATION (US) 1993-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020025523-A1 Probe compositions for chromosome identification and methods INCENP, BOD1L1, SMC2 LMNA 29/4885L3MBTL1 702/4885CETP 3125/4885
US-20110046982-A1 METHODS AND COMPOSITIONS RELATED TO VIRAL INHIBITION EIF2AK2, NSUN2, NSUN3 LMNA 633/4885L3MBTL1 1148/4885CETP 1026/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.