Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 4/20 | 0.58 |
| ▸ | RARA | P10276 | 4/20 | 0.58 |
| ▸ | RARG | P13631 | 10/20 | 0.45 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | GOT1 | P17174 | 1/20 | 0.40 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394320 | 0.91 | RARA (0.58) | IKBKBRARARARGRARBCTNNB1 | |
| SCHEMBL8694764 | 0.91 | RARA (0.68) | IKBKBRARARARGRARBCTNNB1 | |
| SCHEMBL8397886 | 0.91 | RARA (0.66) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL7753722 | 0.87 | RARA (0.53) | IKBKBRARARARGRARBCTNNB1 | |
| SCHEMBL8397839 | 0.86 | IKBKB (0.55) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8431717 | 0.85 | RARA (0.61) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8432432 | 0.85 | RARA (0.61) | IKBKBRARARARGRARBCTNNB1 | |
| SCHEMBL8397783 | 0.85 | RARA (0.56) | IKBKBRARARARGRARBCTNNB1 | |
| SCHEMBL8434728 | 0.84 | RARA (0.60) | IKBKBRARARARGRARBMEN1 | |
| SCHEMBL8394300 | 0.84 | CYP3A4 (0.53) | IKBKBRARARARGLMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877342-A | SKIN DISORDERS; RESPIRATORY SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUIES GALDERMA (FR) | 1999-03-02 | — | — | US | disclosed |