Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.60 |
| ▸ | IKBKB | O14920 | 5/20 | 0.60 |
| ▸ | RARG | P13631 | 9/20 | 0.48 |
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8426173 | 0.93 | RARA (0.70) | RARAIKBKBRARGRARBCYP26A1 | |
| SCHEMBL8397886 | 0.90 | RARA (0.66) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8394253 | 0.87 | IKBKB (0.49) | RARAIKBKBRARGALDH1A1MAPK1 | |
| SCHEMBL8431717 | 0.86 | RARA (0.61) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8432432 | 0.86 | RARA (0.61) | RARAIKBKBRARGRARBCYP26A1 | |
| SCHEMBL8434724 | 0.85 | RARA (0.44) | RARAIKBKBRARGRARBCYP26A1 | |
| SCHEMBL8433279 | 0.85 | RARA (0.62) | RARAIKBKBRARGRARBCYP26A1 | |
| SCHEMBL8424422 | 0.84 | RARA (0.67) | RARAIKBKBRARGRARBMEN1 | |
| SCHEMBL8437028 | 0.84 | RARA (0.49) | RARAIKBKBRARGRARBCYP26A1 | |
| SCHEMBL8436677 | 0.84 | RARA (0.59) | RARAIKBKBRARGRARBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | claimed |
| EP-0776881-B1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CIRD GALDERMA (FR) | 1999-12-08 | — | — | EP | disclosed |
| EP-0776881-A1 | Bi-aromatic compounds comprising an adamantyl group in para-position, pharmaceutical and cosmetic compositions containing them and their utilization | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA (C.I.R.D. GALDERMA) (FR) | 1997-06-04 | — | — | EP | disclosed |