Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8395434 | 0.94 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1NPSR1HSD17B10AR | |
| SCHEMBL8399331 | 0.93 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1NPSR1HSD17B10AR | |
| SCHEMBL8396616 | 0.90 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1NPSR1HSD17B10AR | |
| SCHEMBL8396258 | 0.90 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1NPSR1HSD17B10MAPT | |
| SCHEMBL8397040 | 0.88 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1NPSR1HSD17B10AR | |
| SCHEMBL8395843 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1NPSR1HSD17B10MAPT | |
| SCHEMBL8400489 | 0.85 | MAPK1 (0.44) | SMN1; SMN2ALDH1A1HSD17B10MAPTLMNA | |
| SCHEMBL8400187 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTLMNAMEN1 | |
| SCHEMBL8399091 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1NPSR1MAPTLMNA | |
| SCHEMBL8399169 | 0.85 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1NPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |