Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8397040 | 0.94 | SMN1; SMN2 (0.46) | SMN1; SMN2THRATHRBARALDH1A1 | |
| SCHEMBL8399170 | 0.93 | SMN1; SMN2 (0.41) | SMN1; SMN2THRATHRBARALDH1A1 | |
| SCHEMBL8399279 | 0.90 | AR (0.39) | SMN1; SMN2THRATHRBARALDH1A1 | |
| SCHEMBL8395434 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2ARALDH1A1MAPTHPGD | |
| SCHEMBL8396258 | 0.88 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL8395804 | 0.86 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPTLMNAMEN1KMT2A | |
| SCHEMBL8399138 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL8395843 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2ALDH1A1MAPTLMNANPSR1 | |
| SCHEMBL8396616 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2ARALDH1A1MAPTHPGD | |
| SCHEMBL8399091 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |