Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 4/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | USP5 | P45974 | 2/20 | 0.32 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399179 | 1.00 | ADRA1A (0.34) | ADRA1AHCRTR2USP5TLR9TLR8 | |
| SCHEMBL8399190 | 1.00 | ADRA1A (0.34) | ADRA1AHCRTR2USP5TLR9TLR8 | |
| SCHEMBL8399181 | 1.00 | ADRA1A (0.34) | ADRA1AHCRTR2USP5TLR9TLR8 | |
| SCHEMBL8395151 | 0.90 | SLC6A4 (0.36) | TLR9TLR8TLR7 | |
| SCHEMBL8395150 | 0.90 | SLC6A4 (0.36) | TLR9TLR8TLR7 | |
| SCHEMBL8418729 | 0.88 | OPRL1 (0.33) | ADRA1AHCRTR2TLR9TLR8TLR7 | |
| SCHEMBL8418731 | 0.88 | OPRL1 (0.33) | ADRA1AHCRTR2TLR9TLR8TLR7 | |
| SCHEMBL7757745 | 0.85 | SPHK1 (0.35) | ADRA1AHCRTR2USP5HDAC6HTR2A | |
| SCHEMBL7757746 | 0.85 | SPHK1 (0.35) | ADRA1AHCRTR2USP5HDAC6HTR2A | |
| SCHEMBL8029517 | 0.85 | SPHK1 (0.35) | ADRA1AHCRTR2USP5HDAC6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0630903-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-06-02 | — | — | EP | disclosed |
| US-5454977-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-10-03 | — | — | US | disclosed |
| EP-0630903-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |