Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.31 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8418731 | 1.00 | OPRL1 (0.33) | OPRL1ADRA1AHCRTR2DGAT1SOAT1 | |
| SCHEMBL9008473 | 0.91 | OPRL1 (0.32) | OPRL1DGAT1SOAT1ALDH1A1LMNA | |
| SCHEMBL8015140 | 0.91 | OPRL1 (0.32) | OPRL1DGAT1SOAT1ALDH1A1LMNA | |
| SCHEMBL8015134 | 0.91 | OPRL1 (0.32) | OPRL1DGAT1SOAT1ALDH1A1LMNA | |
| SCHEMBL8015137 | 0.91 | OPRL1 (0.32) | OPRL1DGAT1SOAT1ALDH1A1LMNA | |
| SCHEMBL8399190 | 0.88 | ADRA1A (0.34) | ADRA1AHCRTR2TLR9TLR8TLR7 | |
| SCHEMBL8399181 | 0.88 | ADRA1A (0.34) | ADRA1AHCRTR2TLR9TLR8TLR7 | |
| SCHEMBL8399179 | 0.88 | ADRA1A (0.34) | ADRA1AHCRTR2TLR9TLR8TLR7 | |
| SCHEMBL8399185 | 0.88 | ADRA1A (0.34) | ADRA1AHCRTR2TLR9TLR8TLR7 | |
| SCHEMBL7757723 | 0.86 | CYP2C9 (0.35) | OPRL1ADRA1AHCRTR2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0648773-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 1999-09-08 | — | — | EP | disclosed |
| US-5547606-A | Silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-08-20 | — | — | US | disclosed |
| EP-0648773-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-04-19 | — | — | EP | disclosed |