SCHEMBL8399199

SCHEMBL8399199

CCOC(C)OCC.CCOCOCC

nearest known ligand 0.71

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.71
THRB P10828 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28526086 0.92 LMNA (0.67) LMNATHRB
Ether SCHEMBL491351 0.88 LMNA (0.80) LMNATHRB
SCHEMBL2094168 0.84 LMNA (1.00) LMNATHRB
SCHEMBL9459 0.84
SCHEMBL7457099 0.82 LMNA (0.71) LMNATHRB
SCHEMBL707537 0.82 LMNA (0.71) LMNATHRB
SCHEMBL14848976 0.81 LMNA (0.80) LMNATHRB
SCHEMBL5105333 0.81
Hydrogen Sulfide SCHEMBL3719386 0.81
SCHEMBL2354348 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0642486-B1 PRODUCTION OF HYDROFLUOROCARBONS FROM alpha-FLUOROETHERS AND SOME alpha-FLUOROETHERS ICI PLC (GB) 1999-06-02 EP disclosed
US-5750807-A REACTION OF ALDEHYDE WITH HYDROGEN FLUORIDE FOR FLUORINATION IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1998-05-12 US disclosed
US-5696308-A HEATING AN ALPHA-FLUOROETHER IN THE VAPOR PHASE WITH HYDROGEN FLUORIDE IN THE PRESENCE OF A CATALYST IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1997-12-09 US disclosed
US-5637776-A ACYCLIC FLUORINATED ETHER IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1997-06-10 US disclosed
US-5504263-A HEATING ALPHA-FLUOROETHER IN VAPOR PHASE AT ELEVATED TEMPERATURE INPRESENCE OF HYDROGEN FLUORIDE AND CATALYST IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-04-02 US disclosed
US-4692426-A Phosphite-promoted ruthenium-cobalt catalysts for the dealkoxyhydroxymethylation of acetals to form glycol ethers SUN REFINING AND MARKETING COMPANY (US) 1987-09-08 US disclosed