Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | POLQ | O75417 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399225 | 0.91 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL8399315 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTFDFT1RAB9AMTNR1A | |
| SCHEMBL8398013 | 0.88 | SMN1; SMN2 (0.41) | SMN1; SMN2MAPTALDH1A1RAB9AHTT | |
| SCHEMBL8399140 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTGAAFDFT1ALDH1A1 | |
| SCHEMBL8400188 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EFDFT1ALDH1A1RAB9A | |
| SCHEMBL8400306 | 0.82 | KMT2A (0.43) | SMN1; SMN2ALDH1A1RAB9AHTTTP53 | |
| SCHEMBL8397876 | 0.82 | SMN1; SMN2 (0.40) | SMN1; SMN2KDM4EALDH1A1SIRT2MTNR1A | |
| SCHEMBL8397055 | 0.82 | HTT (0.46) | SMN1; SMN2MAPTKDM4EALDH1A1RAB9A | |
| SCHEMBL8398029 | 0.81 | LTB4R2 (0.42) | SMN1; SMN2FDFT1POLQNPC1MEN1 | |
| SCHEMBL8399042 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP1A2FDFT1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |