Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLQ | O75417 | 1/20 | 0.34 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399264 | 0.90 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9AMEN1KMT2AMAPT | |
| SCHEMBL8399283 | 0.89 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9ATP53MTNR1AMTNR1B | |
| SCHEMBL8397982 | 0.87 | SMN1; SMN2 (0.42) | SMN1; SMN2RAB9ATP53MEN1KMT2A | |
| SCHEMBL8399007 | 0.85 | SMN1; SMN2 (0.37) | SMN1; SMN2TSHRNPSR1KMT2AMAPT | |
| SCHEMBL8400306 | 0.84 | KMT2A (0.43) | SMN1; SMN2RAB9ATP53MEN1KMT2A | |
| SCHEMBL8398029 | 0.83 | LTB4R2 (0.42) | SMN1; SMN2MEN1KMT2ANPC1POLQ | |
| SCHEMBL8399042 | 0.83 | SMN1; SMN2 (0.39) | SMN1; SMN2RAB9ATSHRMTNR1AMTNR1B | |
| SCHEMBL8399140 | 0.83 | SMN1; SMN2 (0.51) | SMN1; SMN2RAB9ATSHRNPSR1MEN1 | |
| SCHEMBL8400465 | 0.83 | MTNR1A (0.52) | RAB9ATP53MTNR1AMTNR1BKMT2A | |
| SCHEMBL8400558 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2TP53TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |