Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLQ | O75417 | 6/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GPX4 | P36969 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8396593 | 0.90 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8400465 | 0.86 | MTNR1A (0.52) | KMT2ANPC1RAB9ATP53 | |
| SCHEMBL8399042 | 0.86 | SMN1; SMN2 (0.39) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8398029 | 0.86 | LTB4R2 (0.42) | KMT2AMEN1SMN1; SMN2NPC1POLQ | |
| SCHEMBL8399140 | 0.86 | SMN1; SMN2 (0.51) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8396315 | 0.86 | SMN1; SMN2 (0.47) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8400558 | 0.85 | SMN1; SMN2 (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL8400188 | 0.85 | SMN1; SMN2 (0.40) | KMT2AMEN1SMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL8399315 | 0.84 | SMN1; SMN2 (0.37) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL8397876 | 0.84 | SMN1; SMN2 (0.40) | KMT2AMEN1SMN1; SMN2ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0647636-B1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | SENJU PHARMA CO (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5532257-A | ENZYME INHIBITOR | SENJU PHARMACEUTICAL CO., LTD (JP) | 1996-07-02 | — | — | US | disclosed |
| EP-0647636-A1 | BENZOTHIAZOLE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Senju Pharmaceutical Co., Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |