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SCHEMBL8399285

SCHEMBL8399285

CO[C@H]1C(=O)N2C(C(=O)C(C)(C)C)=C(C)CS(=O)(=O)[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8399288 1.00 ELANE (1.00) ELANE
SCHEMBL7271423 0.85 ELANE (0.74) ELANE
SCHEMBL7271431 0.85 ELANE (0.74) ELANE
SCHEMBL7271427 0.85 ELANE (0.74) ELANE
SCHEMBL9348330 0.85 ELANE (0.74) ELANE
SCHEMBL9348324 0.85 ELANE (0.74) ELANE
SCHEMBL7436377 0.85 ELANE (1.00) ELANE
SCHEMBL7279397 0.85 ELANE (1.00) ELANE
SCHEMBL7436386 0.85 ELANE (1.00) ELANE
SCHEMBL7970632 0.85 ELANE (1.00) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639195-B1 2-ACYLOXYCEPHEM DERIVATIVES AS ELASTASE INHIBITORS PHARMACIA & UPJOHN SPA (IT) 1999-05-26 — — EP disclosed
US-5587373-A ELASTASE INHIBITORS FARMITALIA CARLO ERBA S.R.L. (IT) 1996-12-24 — — US disclosed
US-5348952-A Antibiotics for antiinflammatory agents, degenerative diseases caused by proteolytic enzymes and respiratory system disorders FARMITALIA CARLO ERBA S.R.L. (IT) 1994-09-20 — — US disclosed
EP-0505413-B1 BETA-LACTAM DERIVATIVES ERBA CARLO SPA (IT) 1994-08-31 — — EP disclosed