Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970632 | 1.00 | ELANE (1.00) | ELANE | |
| SCHEMBL7279397 | 1.00 | ELANE (1.00) | ELANE | |
| SCHEMBL7436386 | 1.00 | ELANE (1.00) | ELANE | |
| SCHEMBL7432470 | 0.86 | ELANE (0.76) | ELANE | |
| SCHEMBL7432478 | 0.86 | ELANE (0.76) | ELANE | |
| SCHEMBL7271778 | 0.86 | ELANE (0.76) | ELANE | |
| SCHEMBL8399288 | 0.85 | ELANE (1.00) | ELANE | |
| SCHEMBL8399285 | 0.85 | ELANE (1.00) | ELANE | |
| SCHEMBL8670544 | 0.84 | ELANE (0.72) | ELANE | |
| SCHEMBL8670547 | 0.84 | ELANE (0.72) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364848-A | Elastase inhibitors | MERCK & CO., INC. (US) | 1994-11-15 | — | — | US | disclosed |
| US-5132301-A | Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents | MERCK & CO., INC. (US) | 1992-07-21 | — | — | US | disclosed |
| EP-0267723-A2 | New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents | MERCK & CO. INC. (US) | 1988-05-18 | — | — | EP | disclosed |