Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL8400986 | 0.99 | CCKBR (0.80) | CCKBR | |
| SCHEMBL8400987 | 0.92 | CCKBR (0.81) | CCKBR | |
| SCHEMBL8403005 | 0.90 | CCKBR (0.75) | CCKBR | |
| SCHEMBL8398590 | 0.89 | CCKBR (1.00) | CCKBR | |
| SCHEMBL9541395 | 0.87 | CCKBR (0.67) | CCKBR | |
| SCHEMBL8404668 | 0.85 | CCKBR (0.80) | CCKBR | |
| SCHEMBL8403200 | 0.83 | CCKBR (0.65) | CCKBR | |
| SCHEMBL9542994 | 0.81 | CCKBR (0.65) | CCKBR | |
| SCHEMBL9541285 | 0.81 | CCKBR (0.79) | CCKBR | |
| SCHEMBL8400996 | 0.79 | MMP2 (0.53) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711283-B1 | TETRAHYDRO-1H-BENZAZEPINONES AND HEXAHYDROAZEPINONES AS SELECTIVE CHOLECYSTOKININ-B RECEPTOR ANTAGONISTS | PFIZER (US) | 1999-06-16 | — | — | EP | disclosed |
| US-5618811-A | Tetrahydro-1H-benzazepinones and hexahydroazepinones as selective cholecystokinin-B receptor antagonists | PFIZER INC. (US) | 1997-04-08 | — | — | US | disclosed |