Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.71 |
| ▸ | MGAM | O43451 | 1/20 | 0.71 |
| ▸ | SI | P14410 | 1/20 | 0.71 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | DHODH | Q02127 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572 | 0.86 | KMT2A (0.58) | GAAMGAMSIMGAM2HSD17B10 | |
| Malonic Acid Diethyl Ester SCHEMBL8636 | 0.84 | GAA (1.00) | GAAMGAMSIMGAM2HSD17B10 | |
| Malonic Acid Diethyl Ester SCHEMBL1331187 | 0.84 | GAA (1.00) | GAAMGAMSIMGAM2HSD17B10 | |
| Malonic Acid Diethyl Ester SCHEMBL1330550 | 0.84 | GAA (1.00) | GAAMGAMSIMGAM2HSD17B10 | |
| Malonic Acid Diethyl Ester SCHEMBL1331824 | 0.84 | GAA (1.00) | GAAMGAMSIMGAM2HSD17B10 | |
| Malonic Acid Diethyl Ester SCHEMBL1864301 | 0.84 | GAA (1.00) | GAAMGAMSIMGAM2HSD17B10 | |
| Malonic Acid Diethyl Ester SCHEMBL28691891 | 0.84 | GAA (0.56) | GAAMGAMSIMGAM2HSD17B10 | |
| SCHEMBL7873229 | 0.82 | GAA (0.48) | GAAMGAMSIMGAM2HSD17B10 | |
| SCHEMBL8142603 | 0.82 | TSHR (0.73) | GAAHSD17B10TSHRALDH1A1KMT2A | |
| SCHEMBL15334365 | 0.82 | GAA (0.52) | GAAMGAMSIMGAM2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5969046-A | USING TERTIARY AMINES AND EPOXIDES AS MAIN ACTIVATOR OF MICHAEL CONDENSATION CURE PROCESS | ROHM AND HAAS COMPANY (US) | 1999-10-19 | — | — | US | disclosed |
| EP-0326723-B1 | METHOD FOR REACTING TWO COMPONENTS, COMPOSITIONS, COATING COMPOSITIONS AND USES THEREOF | ROHM AND HAAS COMPANY (US) | 1993-03-24 | — | — | EP | disclosed |
| EP-0326723-A1 | Method for reacting two components, compositions, coating compositions and uses thereof | ROHM AND HAAS COMPANY (US) | 1989-08-09 | — | — | EP | disclosed |