Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 6/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403926 | 0.88 | KLK7 (0.37) | KLK7OPRD1OPRK1ACHEKLK5 | |
| SCHEMBL8403192 | 0.87 | PRKCA (0.38) | KLK7OPRD1OPRK1ACHEKLK5 | |
| SCHEMBL29202479 | 0.77 | STS (0.39) | KLK7OPRD1OPRK1ACHESTS | |
| SCHEMBL968202 | 0.77 | STS (0.39) | KLK7OPRD1OPRK1ACHESTS | |
| SCHEMBL28941207 | 0.74 | STS (0.40) | OPRD1OPRK1STSUSP30JAK2 | |
| SCHEMBL6364579 | 0.74 | PDE4A (0.38) | KLK7OPRD1OPRK1ACHEKLK5 | |
| SCHEMBL28629670 | 0.74 | PDE4A (0.40) | OPRD1OPRK1ACHESTSPDE4A | |
| SCHEMBL28923042 | 0.74 | PDE4A (0.40) | OPRD1OPRK1ACHESTSPDE4A | |
| SCHEMBL194209 | 0.71 | — | — | |
| SCHEMBL387446 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990165-A | AN UNSATURATED ALPHA-AMINO CARBOXYLIC ACID TO MODIFY NEUROTRANSMISSION BY INTERACTION WITH IONOTROPIC AND MEETABOTROPIC RECEPTORS; CENTRAL NERVOUS SYSTEM DISORDERS; | LILLY, S.A. (ES) | 1999-11-23 | — | — | US | disclosed |