Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 10/20 | 0.48 |
| ▸ | ATP4B | P51164 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | WDR5 | P61964 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6483109 | 0.86 | ATP4A (0.59) | ATP4AATP4BKMT2AWDR5GAA | |
| SCHEMBL6475333 | 0.83 | ATP4A (0.55) | ATP4AATP4BKMT2AGAAMEN1 | |
| Water SCHEMBL6481792 | 0.82 | ATP4A (0.54) | ATP4AATP4BKMT2AGAAMEN1 | |
| SCHEMBL6475793 | 0.81 | ATP4A (0.57) | ATP4AATP4BKMT2AGAAMEN1 | |
| SCHEMBL9677072 | 0.80 | ATP4A (0.46) | ATP4AATP4BKMT2AWDR5GAA | |
| SCHEMBL6475028 | 0.80 | ATP4A (0.57) | ATP4AATP4BKMT2AGAAMEN1 | |
| Water SCHEMBL6484016 | 0.80 | ATP4A (0.56) | ATP4AATP4BKMT2AGAAMEN1 | |
| Water SCHEMBL6484008 | 0.80 | ATP4A (0.56) | ATP4AATP4BKMT2AGAAMEN1 | |
| SCHEMBL6482642 | 0.79 | ATP4A (0.54) | ATP4AATP4BKMT2AGAAMEN1 | |
| SCHEMBL23988442 | 0.79 | WDR5 (0.58) | ATP4AATP4BKMT2AWDR5GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869513-A | ANTIULCER AGENTS | G. D. SEARLE & CO. (US) | 1999-02-09 | — | — | US | claimed |
| US-5869513-A | ANTIULCER AGENTS | G. D. SEARLE & CO. (US) | 1999-02-09 | — | — | US | disclosed |