SCHEMBL8400147

SCHEMBL8400147

CC(=O)O[Si](C)(C)C.CCN(CC)CC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL338658 0.82
SCHEMBL27534844 0.79
SCHEMBL28118443 0.79
SCHEMBL28088714 0.79
Propionic Acid SCHEMBL27990618 0.78 FFAR3 (0.50) ALDH1A1LMNAHSD17B10
Ether SCHEMBL10423293 0.78 ALDH1A1 (0.44) ALDH1A1LMNAHSD17B10
SCHEMBL5395114 0.77 CHRM2 (0.32) ALDH1A1LMNAHSD17B10CHRM2CHRM4
SCHEMBL5389407 0.77 CHRM2 (0.32) ALDH1A1LMNAHSD17B10CHRM2CHRM4
Ethylene SCHEMBL27729664 0.76 ALDH1A1 (0.37) ALDH1A1LMNAHSD17B10
SCHEMBL11601654 0.74 OPRK1 (0.38) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5945518-A Process for the preparation of anthracycline antibiotics Sicor Societa' Italiana Corticosteroida S.p.A. (IT) 1999-08-31 US disclosed
EP-0819132-B1 A PROCESS FOR THE PREPARATION OF ANTHRACYCLINE ANTIBIOTICS SICOR SPA (IT) 1999-06-09 EP disclosed
EP-0819132-A1 A PROCESS FOR THE PREPARATION OF ANTHRACYCLINE ANTIBIOTICS SICOR Società Italiana Corticosteroidi S.p.A. (IT) 1998-01-21 EP disclosed
WO-1996029335-A1 A PROCESS FOR THE PREPARATION OF ANTHRACYCLINE ANTIBIOTICS SICOR SOCIETA' ITALIANA CORTICOSTEROIDI S.P.A. (IT) 1996-09-26 WO disclosed