Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 10/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405165 | 0.80 | CHRM1 (0.52) | CHRM1CHRM4CHRNB2CHRNA4CHRM2 | |
| SCHEMBL9147916 | 0.72 | CHRM1 (0.47) | CHRM1CHRM4CHRNB2CHRNA4CHRM2 | |
| Hydrochloric Acid SCHEMBL9147930 | 0.71 | CHRM1 (0.46) | CHRM1CHRM4CHRNB2CHRNA4CHRM2 | |
| SCHEMBL9772068 | 0.71 | CHRM1 (0.44) | CHRM1CHRM4CHRM2CHRM3CHRM5 | |
| SCHEMBL9151015 | 0.71 | CHRM1 (0.48) | CHRM1CHRM4CHRM2CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL9154554 | 0.70 | CHRM1 (0.47) | CHRM1CHRM4CHRM2CHRM3CHRM5 | |
| SCHEMBL9519154 | 0.69 | CHRM2 (0.40) | CHRM1CHRM4CHRM2CHRM3CHRM5 | |
| SCHEMBL9152324 | 0.68 | CHRM1 (0.44) | CHRM1CHRM4CHRM2CHRM3CHRM5 | |
| SCHEMBL9342927 | 0.68 | CHRNB2 (0.47) | CHRM1CHRM4CHRNB2CHRNA4CHRM2 | |
| SCHEMBL8519452 | 0.68 | CHRM2 (0.51) | CHRM1CHRM4CHRNB2CHRNA4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4925858-A | NERVOUS SYSTEM DISORDERS, ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1990-05-15 | — | — | US | claimed |
| US-RE36374-E | 1,2,3-triazole and tetrazole substituted piperidine or tetrahydropyridine compounds useful as acetylcholine agonists | H. LUNDBECK, A/S (DK) | 1999-11-02 | — | — | US | disclosed |
| US-4925858-A | NERVOUS SYSTEM DISORDERS, ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1990-05-15 | — | — | US | disclosed |
| US-4866077-A | TREATMENT OF NERVOUS SYSTEM DISORDERS SUCH AS ALZHEIMER*S DISEASE | H. LUNDBECK A/S (DK) | 1989-09-12 | — | — | US | disclosed |
| EP-0296721-A2 | Heterocyclic compounds | H. LUNDBECK A/S (DK) | 1988-12-28 | — | — | EP | disclosed |