Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 4/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 5/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914582 | 0.92 | TYR (0.48) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL8400481 | 0.92 | TYR (0.58) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL28858657 | 0.86 | TYR (0.53) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL14023713 | 0.85 | AMY1A (0.50) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL8402868 | 0.85 | TYR (0.71) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL9504248 | 0.85 | TYR (0.71) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL8590686 | 0.85 | TYR (0.71) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL3358965 | 0.85 | TYR (0.71) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL7032757 | 0.84 | TRPA1 (0.50) | TYRALOX15MEN1TP53CYP3A4 | |
| SCHEMBL1272901 | 0.84 | TYR (0.50) | TYRALOX15MEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017204-A1 | EFFICIENT AND COST-EFFECTIVE PROCESS FOR THE MANUFACTURE OF AMYL M-CRESOL | AESICA PHARMACEUTICALS LIMITED (GB) | 2012-02-09 | — | — | WO | disclosed |