Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.31 |
| ▸ | ESRRA | P11474 | 1/20 | 0.31 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23638712 | 0.94 | NPC1 (0.37) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL11136454 | 0.89 | NPC1 (0.41) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL31651454 | 0.84 | MAPK14 (0.34) | NPC1RAB9ALMNAKDM4ESMN1; SMN2 | |
| SCHEMBL373843 | 0.83 | NPC1 (0.35) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL7177419 | 0.83 | THRB (0.39) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL29613654 | 0.83 | NPC1 (0.35) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL21586965 | 0.83 | NPC1 (0.40) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL21586947 | 0.83 | PDE2A (0.36) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL30887157 | 0.83 | PDE2A (0.36) | NPC1RAB9ALMNAKDM4EALDH1A1 | |
| SCHEMBL8441278 | 0.83 | CA1 (0.39) | NPC1RAB9ALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0488145-B1 | Ultraviolet light absorbing intraocular lens | MENICON CO LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5147902-A | Benzotriazole compound | MENICON CO., LTD. (JP) | 1992-09-15 | — | — | US | disclosed |
| EP-0488145-A2 | Ultraviolet light absorbing ocular lens | Menicon Co., Ltd. (JP) | 1992-06-03 | — | — | EP | disclosed |