Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 14/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.59 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28266121 | 0.91 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL247446 | 0.91 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL27458661 | 0.82 | PDE4A (0.57) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL8999182 | 0.80 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL127734 | 0.80 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL24704167 | 0.80 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL127735 | 0.80 | PDE4A (0.56) | PDE4APDE4BPDE4CPDE4DCYP3A4 | |
| SCHEMBL8999173 | 0.80 | PDE4A (0.60) | PDE4APDE4BPDE4CPDE4DPOLB | |
| SCHEMBL9519781 | 0.79 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL24704163 | 0.76 | TBXAS1 (0.54) | PDE4APDE4BPDE4CPDE4DPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640586-B1 | STILBENE DERIVATIVE AND STILBENE ANALOG DERIVATIVE, AND USE THEREOF | MORINAGA MILK INDUSTRY CO LTD (JP) | 1999-06-09 | — | — | EP | disclosed |
| US-5589506-A | ENZYME INHIBITORS FOR LIPOXYGENASE | MORINAGA MILK INDUSTRY CO., LTD. (JP) | 1996-12-31 | — | — | US | disclosed |