SCHEMBL8400815

SCHEMBL8400815

Bc1c(C)cc(-c2cc(C)c(B)c(C)c2)cc1C

nearest known ligand 0.47

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.47
CYP3A4 P08684 2/20 0.47
TSHR P16473 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
TP53 P04637 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29016339 0.80 ALDH1A1 (0.42) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL339301 0.79 RAPGEF4 (0.45) ALDH1A1TSHRTDP1TP53CA1
SCHEMBL28885930 0.76 RAPGEF4 (0.43) ALDH1A1TSHRTDP1TP53CA1
Bromide SCHEMBL28225185 0.76 RAPGEF4 (0.43) ALDH1A1TSHRTDP1TP53CA1
Fluoride SCHEMBL27746806 0.76 RAPGEF4 (0.43) ALDH1A1TSHRTDP1TP53CA1
SCHEMBL23581648 0.76 RAPGEF4 (0.43) ALDH1A1TSHRTDP1TP53CA1
Hydrochloric Acid SCHEMBL28495688 0.76 RAPGEF4 (0.43) ALDH1A1TSHRTDP1TP53CA1
SCHEMBL21360879 0.74 CYP3A4 (0.35) CYP3A4TSHR
SCHEMBL10290767 0.73 ALDH1A1 (0.47) ALDH1A1CYP3A4TSHRTDP1TP53
SCHEMBL23961452 0.73 NQO2 (0.35) ALDH1A1CYP3A4TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120129076-A1 Novel Sulfonic Acid Group-Containing Segmented Block Copolymer and Use Thereof TOYO BOSEKI KABUSHIKI KAISHA (JP) 2012-05-24 US disclosed