Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1580188 | 0.92 | TSHR (0.34) | TSHRMAPT | |
| SCHEMBL841034 | 0.84 | TSHR (0.39) | TSHRMAPTNPC1RAB9ACYP19A1 | |
| SCHEMBL27849345 | 0.83 | MAPK1 (0.39) | TSHR | |
| SCHEMBL841537 | 0.82 | — | — | |
| SCHEMBL1579855 | 0.76 | — | — | |
| SCHEMBL841429 | 0.71 | TSHR (0.50) | TSHRMAPTNPC1RAB9ACYP19A1 | |
| SCHEMBL841546 | 0.69 | — | — | |
| SCHEMBL9397850 | 0.67 | TSHR (0.50) | TSHRMAPTNPC1RAB9ACYP19A1 | |
| SCHEMBL8736449 | 0.67 | MAPK1 (0.41) | — | |
| SCHEMBL841793 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2310446-B1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-23 | — | — | EP | claimed |
| CN-102177197-B | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2013-11-06 | — | — | CN | claimed |
| US-8143336-B2 | Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-27 | — | — | US | claimed |
| CN-102177197-A | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2011-09-07 | — | — | CN | claimed |
| EP-2310446-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | Momentive Performance Materials Inc. (US) | 2011-04-20 | — | — | EP | claimed |
| WO-2010017370-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2010-02-11 | — | — | WO | claimed |
| US-20100036018-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-02-11 | — | — | US | claimed |
| EP-2310446-B1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE | MOMENTIVE PERFORMANCE MAT INC (US) | 2015-12-23 | — | — | EP | disclosed |
| CN-102177197-B | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2013-11-06 | — | — | CN | disclosed |
| US-8143336-B2 | Activated halo-containing aralkylsilane composition, process of preparing same and rubber compositions made therefrom | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2012-03-27 | — | — | US | disclosed |
| CN-102177197-A | Activated halo-containing aralkylsilane | MOMENTIVE PERFORMANCE MAT INC | 2011-09-07 | — | — | CN | disclosed |
| US-20100036018-A1 | ACTIVATED HALO-CONTAINING ARALKYLSILANE COMPOSITION, PROCESS OF PREPARING SAME AND RUBBER COMPOSITIONS MADE THEREFROM | MOMENTIVE PERFORMANCE MATERIALS INC. | 2010-02-11 | — | — | US | disclosed |