SCHEMBL8736449

SCHEMBL8736449

CCO[Si](OCC)(OCC)C(C)(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 2/20 0.39
TAAR1 Q96RJ0 1/20 0.39
ALOX15 P16050 1/20 0.39
KCNN4 O15554 1/20 0.38
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
HDAC3 O15379 1/20 0.34
HDAC4 P56524 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC2 Q92769 1/20 0.34
HDAC10 Q969S8 1/20 0.34
HDAC11 Q96DB2 1/20 0.34
HDAC8 Q9BY41 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716560 0.85 MAPK1 (0.43) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL30392076 0.84 MAPK1 (0.39) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL6512003 0.83 MAPK1 (0.41) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL9716571 0.82 MAPK1 (0.40) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL6332001 0.81 KCNN4 (0.39) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL27849345 0.80 MAPK1 (0.39) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL27908528 0.80 CYP2C19 (0.42) ALDH1A1ALOX15KCNN4CHRM2CHRM4
SCHEMBL10628347 0.79 MAPK1 (0.38) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL10627099 0.79 MAPK1 (0.38) MAPK1ALDH1A1TAAR1ALOX15KCNN4
SCHEMBL27791293 0.79 MAPK1 (0.38) MAPK1ALDH1A1TAAR1ALOX15KCNN4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693524-B1 Polypropylene resin and film prepared therefrom IDEMITSU PETROCHEMICAL CO (JP) 1998-06-10 EP disclosed
EP-0693524-A1 Polypropylene resin and film prepared therefrom IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1996-01-24 EP disclosed