Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23510722 | 0.84 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL11842169 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL11842159 | 0.83 | MEN1 (0.57) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL23510741 | 0.80 | TP53 (0.47) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL3919033 | 0.80 | MEN1 (0.54) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL29661574 | 0.78 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL10709649 | 0.76 | MEN1 (0.54) | MEN1KMT2AALDH1A1GLATSHR | |
| Hydrochloric Acid SCHEMBL11183161 | 0.75 | MEN1 (0.49) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL1520370 | 0.75 | MEN1 (0.66) | MEN1KMT2AALDH1A1GLATSHR | |
| SCHEMBL145553 | 0.75 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1GLATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0918460-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-06-02 | — | — | EP | disclosed |
| WO-1998004131-A1 | METHODS OF TREATMENT OF EYE TRAUMA AND DISORDERS | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1998-02-05 | — | — | WO | disclosed |