Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231959 | 0.93 | LMNA (0.44) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL15757375 | 0.92 | LMNA (0.49) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL8531514 | 0.84 | FOLH1 (0.41) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL10190942 | 0.81 | PAOX (0.40) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL7687386 | 0.77 | LMNA (0.65) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL5314758 | 0.76 | FOLH1 (0.43) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL24003308 | 0.72 | LMNA (0.59) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL6938450 | 0.71 | LMNA (0.65) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL11329424 | 0.70 | KDM5A (0.61) | LMNATDP1HSD17B10TSHRPMP22 | |
| SCHEMBL22140615 | 0.70 | LMNA (0.52) | LMNATDP1HSD17B10TSHRPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11269171-A | — | — | None | — | — | JP | disclosed |
| JP-H11269171-A | THERAPEUTIC AGENT FOR FAT METABOLIC DISORDER COMPRISING 5-(1,2-DITHIOLAN-3-YL-)VALERIC ACID (ALPHA-LIPOIC ACID) OR ITS PHYSIOLOGICALLY ACCEPTABLE SALT AS ACTIVE INGREDIENT | BIRD BEROLINA INNOV RES & DEV GMBH | 1999-10-05 | — | — | JP | disclosed |